The Double Role of Nutrients in
Immunity
Gheorghe GIURGIU1,
Manole COJOCARU2
1 Deniplant-Aide Sante
Medical Center, Biomedicine, Bucharest, Romania, deniplant@gmail.com;
https://orcid.org/0000-0002-5449-2712
2 Titu Maiorescu University, Faculty of Medicine, Bucharest,
Romania, cojocaru.manole@gmail.com
Abstract: Background Nutrients are the
substances found in food which drive biological activity, and are essential for
the human body. Dietary nutrients may be converted into metabolites by
intestinal microbes that serve as biologically active molecules affecting
regulatory functions in the host.
Objectives
To demonstrate role of nutrients as functional foods in the management of
immunity.
Materials
and methods This includes the role of macronutrients, micronutrients, and the
gut microbiome in mediating immunological effects. Nutritional modulation of
the immune system has applications within the clinical setting, but can also
have a role in healthy populations, acting to reduce or delay the onset of immune-mediated
chronic diseases. Ongoing research in this field will ultimately lead to a
better understanding of the role of diet and nutrients in immune function
Results
Probiotics may restore the composition of the gut microbiome and introduce
beneficial functions to gut microbial communities, resulting in amelioration or
prevention of gut inflammation and other intestinal or systemic disease phenotypes.
A well-functioning immune system is critical for survival. The immune system
must be constantly alert, monitoring for signs of invasion or danger. Cells of
the immune system must be able to distinguish self from non-self and
furthermore discriminate between non-self molecules
which are harmful (e.g., those from pathogens) and innocuous non-self molecules (e.g., from food).
Conclusion
This presentation describes how diet and intestinal luminal conversion by gut
microbes play a role in immune-mediated chronic diseases.
Key
words: nutrients, gut
microbiota, immunomodulation
DOI
https://doi.org/10.56082/annalsarscibio.2023.1.118
